X-linked Intellectual Disability
X-linked Mental Retardation
📋Overview
X-linked intellectual disability (XLID) refers to a group of genetic disorders characterized by intellectual disability caused by mutations in genes located on the X chromosome. It is a legacy term encompassing multiple distinct conditions with varying features. Modern classification identifies specific syndromes and gene mutations responsible for XLID, such as Fragile X syndrome, which is the most common form. These disorders primarily affect males due to the presence of a single X chromosome, while females may be carriers with milder or no symptoms.
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